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Updated: Jun 17, 2026

Glutamate and Hypoxia as a Stress Model for the Isolated Perfused Vertebrate Retina
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在小鼠杆中,EAAT5谷氨酸转运体快速结合具有微分子亲和力的谷氨酸

Wallace B Thoreson1,2, Bhavana Chhunchha1

  • 1Department of Ophthalmology and Visual Sciences, Truhlsen Eye Institute, Omaha, NE, USA.

The Journal of general physiology
|July 21, 2023
PubMed
概括

棒光受体的反应取决于谷氨酸运输体. 在体内研究表明,小鼠中的EAAT5 (刺激性氨基酸载体5) 迅速激活,但容量有限,这表明质吸收对高谷氨酸释放至关重要.

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Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...