相关实验视频

Updated: Jul 22, 2025

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Published on: June 8, 2019

乳腺癌中的分子残留疾病:检测和治疗拦截

Arielle J Medford¹, Beverly Moy¹, Laura M Spring¹

¹Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts.

Clinical cancer research : an official journal of the American Association for Cancer Research

|July 21, 2023

概括

通过循环瘤DNA (ctDNA) 检测分子残留疾病 (MRD) 显示出与乳腺癌复发有很强的联系. 目前正在进行的试验正在调查基于MRD检测的向治疗是否可以改善患者的治疗结果.

科学领域:

在瘤学瘤学.
分子诊断学分子诊断
基因组学就是基因组学.

背景情况:

乳腺癌是女性癌症死亡的主要原因,转移性复发是治疗后的重大挑战.
目前的监测依赖于症状呈现或不频繁的成像,缺乏敏感的早期检测方法.
循环瘤DNA (ctDNA) 为检测癌症复发提供了一个有前途的基于血液的生物标志物.

结论:

通过ctDNA测试检测MRD代表了乳腺癌治疗后监测的重大进展.
目前正在进行的临床试验对于确定MRD引导的治疗策略是否能改善生存率并减少复发至关重要.
对MRD测定和向治疗的进一步研究有望为个性化乳腺癌管理提供潜力.

更多相关视频

Monitoring of Nanodrug Accumulation in Murine Breast Cancer Metastases

Monitoring of Nanodrug Accumulation in Murine Breast Cancer Metastases

Published on: August 23, 2024

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models

Published on: April 1, 2022

相关概念视频

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...