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减肥手术后的认知控制和减肥:巴里科研究
Emma Custers1,2,3, Debby Vreeken1,2,3, Lisa-Katrin Kaufmann3
1Department of Medical Imaging, Anatomy, Preclinical Imaging Centre, Radboud University Medical Center, Nijmegen, The Netherlands.
Obesity surgery
|July 21, 2023
概括
通过Stroop任务测量的认知控制没有预测Roux-en-Y胃旁路手术 (RYGB) 后的体重减轻. 需要进行更长的随访时间的进一步研究,以了解减肥手术患者的这种关系.
科学领域:
- 神经科学是一个神经科学.
- 肥胖问题研究研究
- 手术科学 手术科学
背景情况:
- 减肥手术 (BS) 是对肥胖的关键治疗方法,但结果各不相同.
- 一些患者经历了手术后不够的减肥,需要对影响因素进行调查.
- 在Roux-en-Y胃绕道术 (RYGB) 后认知控制在减肥中的作用仍然不清楚.
研究的目的:
- 为了研究认知控制和减肥结果之间的关联,RYGB.
- 为了确定基线认知表现是否预测减肥手术后的减肥成功.
主要方法:
- 一项探索性观察性研究涉及35-55岁的参与者,他们有资格参加RYGB.
- 评估身体体重,BMI变化,以及手术前和手术后的总体体重减轻率 (%TBWL).
- 在功能神经成像 (fMRI) 期间使用Stroop任务对认知控制的基线评估,以评估认知干扰的抑制.
主要成果:
- 62名参与者完成了fMRI分析;平均年龄为45.0±5.9岁,手术前BMI为40.2±3.3kg/m2.
- 在RYGB后的一年,平均BMI下降为13.8 ± 2.5 kg/m2,平均%TBWL为34.9 ± 6.3%.
- 斯特鲁普任务的表现,大脑激活和连接性与减肥指标 (delta BMI,%TBWL) 不相关.
结论:
- 认知控制能力似乎无法预测RYGB手术后的体重减轻.
- 未来的研究应该探索更长的随访期,以阐明认知控制和减肥手术结果之间的关系.
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