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Updated: Jul 22, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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在前列腺癌中激活BRAF变化的独特光谱

Alex Chehrazi-Raffle1, Hanna Tukachinsky2, Eamon Toye3

  • 1City of Hope Comprehensive Cancer Center, Duarte, California.

Clinical cancer research : an official journal of the American Association for Cancer Research
|July 21, 2023
PubMed
概括

在大约3%的前列腺癌中发生BRAF变异,主要是II类突变和重组,而不是V600突变. 这种独特的BRAF激活模式需要进一步研究针对MAPK通路的向疗法.

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