与实施干预措施相关的障碍和促进者,以支持在学术和社区癌症中心设置中的口腔抗癌剂坚持
Benyam Muluneh1,2, Michele A Muir1, James Bernard Collins1
1Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
PloS one
|July 21, 2023
概括
在癌症护理中实施口服抗癌剂 (OAA) 药物坚持干预措施面临诸如低意识和复杂设计等挑战. 然而,行政支持和药剂师价值可以促进成功.
科学领域:
- 在瘤学瘤学.
- 实施科学 实施科学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 口服抗癌剂 (OAAs) 越来越多地用于慢性白血病.
- 有效的药物坚持对于OAA疗效和患者的治疗结果至关重要.
- 实施坚持干预的障碍和促进者需要识别.
研究的目的:
- 确定在OAAs上为癌症患者实施药物坚持干预措施的障碍和促进者.
- 为制定有效的坚持支持策略提供信息.
主要方法:
- 使用基于实施研究综合框架 (CFIR) 的半结构化指南进行定性访谈.
- 对参与OAA护理的临床医生和管理人员进行有目的的抽样.
- 对采访进行分析,以确定实施决定因素.
主要成果:
- 关键障碍包括对干预措施的认识不足,坚持测量困难,干预设计复杂性和竞争优先级.
- 促进者包括行政支持,对药剂师角色的认可和对变化的开放.
- 建议包括标准化工作流程,指定冠军和改善沟通.
结论:
- 个人和系统层面的因素对药物坚持干预措施的实施有重大影响.
- 需要一个多学科的方法来设计和实施有效的OAA治疗的坚持策略.
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