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改进了用于心肌T1映射的K空间插曲组合 (SMS-COOKIE) 的同时多切片成像

Ömer Burak Demirel^1,2, Sebastian Weingärtner³, Steen Moeller²

¹Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America.

|July 21, 2023

概括

一种新的心脏磁共振成像 (CMR) 重建方法,SMS-COOKIE,改善图像质量并减少噪音. 与现有技术相比,这种方法在心肌T1映射中提供了较低的空间可变性.

科学领域:

医疗成像医学成像
心血管成像 - 心血管成像
磁共振成像 (MRI) 是一种磁共振成像技术.

背景情况:

心脏磁共振成像 (CMR) 在心血管诊断中起着至关重要的作用.
同时多切片 (SMS) 成像加速CMR采集,但可能影响图像质量.
像SPIRiT和GRAPPA这样的现有重建方法在降低噪音和空间可变性方面存在局限性.

研究的目的:

开发和评估一种新的规范化同时多切片 (SMS) 重建技术,用于增强CMR.
引入SMS与K空间Interpolations (SMS-COOKIE) 的组合,将SPIRiT和GRAPPA的优势与规范化相结合.
评估SMS-COOKIE的性能,特别是其对心肌T1映射准确性和一致性的影响.

主要方法:

开发了SMS-COOKIE,这是一种结合SPIRiT和分割切片GRAPPA原理的重建方法,可选规范化.
实现了带有和没有Locally Low Rank (LLR) 正规化的SMS-COOKIE.
在加快的CMR数据上使用和脉冲准备心率独立反转恢复 (SAPPHIRE) 序列验证了该方法.

主要成果:

有或没有规范化的SMS-COOKIE实现了与单频段成像相比较的T1值.
与RO-SENSE-GRAPPA和分片-GRAPPA (P < 10-4) 相比,SMS-COOKIE在心肌T1的空间变异性明显较低.
LLR规范化进一步降低了空间变异性,显示出与现有方法相比的显著改善 (P < 10-4).

结论:

建议的SMS-COOKIE重建方法可以提高CMR图像质量.
与传统技术相比,SMS-COOKIE显著降低了心肌T1映射的空间变化.
规范化的SMS-COOKIE为加速CMR提供了一个有希望的进步,特别是用于定量T1映射.

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