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Updated: Jul 22, 2025

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NOTCH4通过AP1和IRF4-JMJD3轴增强M2替代巨细胞中IL-13诱导的遗传程序

Susana López-López1,2, María José Romero de Ávila1, María Julia González-Gómez1

  • 1CRIB/Biomedicine Unit, Medical School, University of Castilla-La Mancha/CSIC, C/Almansa 14, 02008 Albacete, Spain.

International immunology
|July 21, 2023
PubMed
概括

介素-13 (IL-13) 信号激活M2巨细胞,但过度激活会导致喘. 这项研究确定NOTCH4受体是这个过程中的关键调节器,这表明它是过敏呼吸道炎症的潜在治疗标.

关键词:
它们有IL-13和IL-13.在NOTCH4中,其他替代性巨细胞.这是一种炎症炎症炎症炎症.巨细胞激活活动

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