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在中风患者中受影响和不受影响四肢之间的骨肌肉纤维特征的差异:一个范围审查
Kenneth S Noguchi1, Jonathan C Mcleod2, Stuart M Phillips2
1School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
卒中幸存者可能会在受影响的肢体中转向更多的II型肌肉纤维. 证据表明,这些II型纤维的潜在缩,影响强度和功率.
科学领域:
- 神经学 神经学
- 运动生理学 运动生理学
- 康复科学 康复科学 康复科学
背景情况:
- 脑卒中显著影响运动功能,导致肌肉衰弱和运动能力下降.
- 骨肌肉的适应,特别是纤维类型比例和横截面积 (CSA),对于中风后的恢复和功能至关重要.
研究的目的:
- 系统地审查和识别有关骨肌肉纤维类型比例和中风后CSA变化的知识差距.
- 描述有关中风患者肌肉适应现有的文献.
主要方法:
- 通过使用多个数据库 (EMBASE,MEDLINE,PsycINFO,CINAHL,SPORTDiscus,Web of Science) 进行了全面的范围审查.
- 从开始到2022年12月20日进行系统搜索,对中风幸存者的肌肉纤维类型和CSA进行研究.
- 数据的提取和合成由两个独立的审稿人进行,结果根据现有理论进行解释.
主要成果:
- 审查包括13项研究,共115名参与者,主要是案例研究和具有小样本的大小的横截面设计.
- 所有研究都分析了肌肉纤维类型分布,而6个研究也检查了CSA.
- 大多数研究 (69%) 表明,肢体中II型肌肉纤维的比例较高,CSA变化的结果各不相同,包括II型纤维缩的证据.
结论:
- 现有证据表明,在中风后的肌肌肉中,II型肌肉纤维的比例更高.
- 虽然CSA变化不一致,但有一些迹象表明II型肌肉纤维的偏好性缩.
- 这些肌肉纤维变化可能会导致中风幸存者的力量和功率缺陷,这表明针对II型纤维大小的干预措施可能会带来潜在的好处.
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