不同的神经反协议对ADHD中抑制反应的神经机制的明显影响
Anna Marie Neuhäußer1, Annet Bluschke1, Veit Roessner1
1Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Germany.
概括
针对或贝塔脑波的不同神经反协议在改善ADHD儿童的反应抑制方面表现出不同的效果. 提升theta功率特别增强了与抑制控制相关的神经活动.
科学领域:
- 神经科学是一个神经科学.
- 儿童和青少年精神病学
- 认知心理学 认知心理学
背景情况:
- 注意缺陷/多动障碍 (ADHD) 经常以受损的响应抑制为特征.
- 脑电图 (EEG) - 神经反 (NF) 是一种潜在的非药物治疗ADHD的方法.
- 标准的theta-down/beta-up (↓θ↑β) NF协议可能不是解决抑制性缺陷的最有效方法.
研究的目的:
- 研究不同EEG神经反协议对ADHD儿童和青少年抑制控制的影响.
- 为了比较训练的效果theta上调,β上调,以及结合的theta/β协议对响应抑制.
主要方法:
- 64名患有ADHD的儿童和青少年参加了三个NF训练条件.
- 神经生理学参数使用前后设计中的Go/Nogo任务进行评估.
- 将ADHD对照组和典型发育的对照组进行了比较.
主要成果:
- 所有检查的NF协议都导致了相似的响应抑制的改善.
- 这些改进背后的神经生理机制在各个方案之间存在显著差异.
- 升调节特别增加了Nogo-P3的振幅,表明它对抑制控制有针对性的作用.
结论:
- 针对和β功率的不同EEG神经反协议显示出不同的神经机制来改善ADHD的响应抑制.
- 与β上调或组合协议相比,theta上调似乎在抑制控制上提供了更具体的神经效应.
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