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合成和抗菌活动的baulamycin A启发衍生物的合成和抗菌活动

Namkyoung Kim1, Sandip Sengupta2, Jiwon Lee3

  • 1KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea; Chemical Kinomics Research Center, Korea Institute of Science and Technology (KIST), 5 Hwarangro 14-gil, Seongbuk-gu, Seoul, 02792, Republic of Korea; Severance Biomedical Science Institute, Graduate School of Medicinal Science, Brain Korea 21 Project, Yonsei University College of Medicine, 50, Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

European journal of medicinal chemistry
|July 21, 2023
PubMed
概括

新的baulamycin A类似物显示出作为MRSA治疗的希望. 这些化合物抑制了必要的细菌酶,破坏了细胞壁,为抗药性感染提供了潜在的抵抗力.

关键词:
巴乌氨酸A是一种氨酸.甲基西林耐药黄金葡萄球菌 (MRSA)这是SbnE.这就是Siderophore.

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