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简单的方法用于稳定突变的高通量识别

Signe Christensen1, Camille Wernersson1, Ingemar André1

  • 1Department of Biochemistry and Structural Biology, Lund University, Lund, Sweden.

Journal of molecular biology
|July 21, 2023
PubMed
概括

一种新的高通量测试可以识别增加稳定性的蛋白质突变. 这种方法使用深度突变扫描,细胞分类和测序来找到稳定变异,帮助蛋白质工程.

关键词:
深度突变扫描 (deep mutational scanning) 是一种对突变进行深度扫描的方法.一个折叠的记者高通量选的高通量选多重测试多重测试方法热稳定性 热稳定性

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