角质和连接组织过宽度的全身表现之间的关联
Margarita Safir1, Alexandra Satanovsky2, Idan Hecht3
1Ophthalmology Department, Shamir Medical Center, Zerifin, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Military Medicine, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
角与全身组织过宽度有关,特别影响膝盖,脚,脊柱和腹部. 这表明,角质可能源于一种普遍的结缔组织疾病,而不仅仅是眼睛疾病.
科学领域:
- 眼科医生 眼科 眼科
- 遗传学 是一个遗传学.
- 整形外科 整形外科 整形外科
背景情况:
- 角是一种渐进的眼睛疾病.
- 系统性结合组织疾病与过宽松性有关.
- 角质和通用组织过宽度之间的联系需要进一步调查.
研究的目的:
- 调查角和组织过宽松性的全身表现之间的相关性.
- 为了确定角是否与骨科形和有关.
主要方法:
- 一项横截面研究分析了以色列青少年和年轻成年人的940,763份医疗记录.
- 在患有带损伤,骨科形和的个体之间,与没有带的人之间的患病率进行了比较.
- 用单变量和多变量分析来测试关联.
主要成果:
- 角质的患病率为0.16% (1,529例).
- 患有角膜的患者表现出明显更高的 genu varum/valgus,pes planus,脊椎病以及带/带的发病率.
- 关节损伤与角质没有显著的关联.
结论:
- 在膝盖,脚,脊柱和腹部的角质和结缔组织过宽度之间存在显著的关联.
- 这些发现支持假设,角可能是一个普遍结合组织疾病的表现.
- 应该考虑在全身结合性组织异常的范围内的角.
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