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Updated: Jul 22, 2025

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
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STAG2 失活会重新编程 BRAF 突变甲状腺癌细胞的谷氨酸代谢

Xinru Li1,2, Yan Liu1, Juan Liu1

  • 1Key Laboratory for Tumor Precision Medicine of Shaanxi Province and Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, PR China.

Cell death & disease
|July 21, 2023
PubMed
概括

甲状腺癌中的STAG2下调不会影响BRAF突变细胞的增殖,但会增强对谷氨酸缺乏的敏感性. 这通过降低c-Myc的稳定性,损害谷氨酸代谢,并提供新的治疗策略来实现.

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