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Updated: Jun 14, 2026

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注意缺陷/多动障碍 (ADHD) 中的白质变化:对129项扩散成像研究进行了系统的审查,并进行了元分析

Valeria Parlatini^1,2,3, Takashi Itahashi⁴, Yeji Lee^5,6

¹Sackler Institute of Translational Neurodevelopment, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 8AF, London, UK. valeria.parlatini@kcl.ac.uk.

Molecular psychiatry

|July 21, 2023

概括

注意缺陷/多动障碍 (ADHD) 显示了白质连接的改变,特别是在体. 在ADHD中,这些大脑差异可能受到研究质量和参与者的年龄的影响.

科学领域:

神经成像是一种神经成像.
神经科学是一个神经科学.
精神病学是一个精神病学.

背景情况:

注意缺陷/多动障碍 (ADHD) 与扩散加权成像 (DWI) 研究中关于大脑连接的不一致发现有关.
进行了系统性审查和元分析,以解决ADHD的DWI研究中的不一致性.

结论:

建议在ADHD中与认知和运动功能相关的后半球间连接中出现突出的变化.
研究质量,特别是获取参数和预处理,显著影响研究结果.
方法和临床人口统计学变化对未来ADHD神经成像研究的一致性和可比性构成挑战.

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Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.