全球肺癌负担:当前状况和未来趋势
Amanda Leiter1, Rajwanth R Veluswamy2,3, Juan P Wisnivesky4
1Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. amanda.leiter@mssm.edu.
Nature reviews. Clinical oncology
|July 21, 2023
概括
肺癌仍然是一个全球性的健康危机,吸烟是主要的原因. 通过低剂量CT查的早期检测可以通过及时治疗显著降低肺癌死亡率.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 肺癌是全球癌症死亡的主要原因,全球的发病率和死亡率存在显著差异.
- 风险因素包括吸烟,环境暴露 (生物质燃料,石棉,,) 和遗传倾向.
- 吸烟模式受到性别和经济发展的影响,严重影响肺癌趋势.
研究的目的:
- 为全球肺癌流行病学提供全面的概述.
- 讨论关键的肺癌风险因素和全球风险降低策略.
- 总结目前的肺癌查政策及其全球实施情况.
主要方法:
- 对肺癌查的大型队列临床研究的综述.
- 对肺癌发病率和死亡率的全球流行病学数据的分析.
- 审查烟草控制战略和环境风险因素的贡献.
主要成果:
- 低剂量计算机断层扫描 (CT) 查已被证明可以降低肺癌死亡率.
- 查有助于更早的诊断和治疗,显著改善结果.
- 针对高风险个体的建议和全球查实施的增加正在出现.
结论:
- 烟草控制对于减少全球肺癌死亡率至关重要.
- 环境和职业因素导致特定地区的肺癌负担.
- 低剂量CT查是早期检测和降低死亡率的重要工具,全球采用范围正在扩大.
相关概念视频
Other Pulmonary Disorders
873
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
873
Statistical Methods for Analyzing Epidemiological Data
417
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
417
Pulmonary Tuberculosis II
266
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
266
Cancer Prevention
6.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.2K
Targeted Cancer Therapies
7.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.7K
Pulmonary Tuberculosis I
270
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
270


