老年患者爆发抑制和术后妄想之间的相关性:一项前性研究
Shengjie Ren1,2, Chuanbo Zang1, Fang Yuan3
1School of Anesthesiology, Weifang Medical University, Weifang, 261053, China.
Aging clinical and experimental research
|July 21, 2023
概括
在老年手术患者中,手术内突发抑制 (BS) 与手术后狂妄症 (POD) 的更高风险有关. 脆弱的老年患者更容易患BS,这表明BS可以预测POD.
科学领域:
- 麻醉学 麻醉学
- 老年医学 老年医学
- 神经科学是一个神经科学.
背景情况:
- 手术后妄 (POD) 是老年手术患者的一个重大问题.
- 在手术期间的脑电图 (EEG) 监测可以检测突发抑制 (BS),一个特定的EEG模式.
研究的目的:
- 为了研究手术内突发抑制 (BS) 和手术后狂妄症 (POD) 在经历腰部内固定手术的老年患者的发生率之间的关联.
- 在这个患者群体中确定POD的潜在预测因子.
主要方法:
- 研究了一组90名老年患者 (60岁以上) 接受腰部内部固定手术.
- 根据手术内EEG监测,患者被分为爆发抑制 (BS) 和非爆发抑制 (NBS) 组.
- 使用混乱评估方法 (CAM) 评估了手术后妄想.
主要成果:
- 高度虚弱的老年患者在BS组中更为普遍 (P=0.048).
- 在手术内BS和POD之间发现了显著的相关性 (OR:4.954,P=0.045).
- 在BS群中,大多数POD病例表现出过度活跃的亚型.
结论:
- 术内爆发抑制与老年患者术后妄想症的风险增加有关.
- 患有虚弱的老年患者更容易患上手术内BS.
- 术后BS可以作为术后痴呆症的预测标记.
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