空气污染和对中国兰州过敏鼻炎的门诊访问之间的联系
Jie Ji1, Kangbing Chen2, Jiyuan Dong3
1Department of Otorhinolaryngology Head and Neck Surgery, The First People's Hospital of Lanzhou, Lanzhou, 730000, People's Republic of China. yuiopdongjiyuan@163.com.
概括
短期暴露于空气污染,包括PM2.5和臭氧,显著增加了兰州的过敏性鼻炎 (AR) 门诊访问. 男人和成年人表现出更高的敏感性,影响因季节和污染物而异.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 新出现的证据将短期空气污染暴露与过敏性鼻炎 (AR) 联系起来.
- 对中国的研究有限且不一致.
- 中国兰州为本次调查提供了具体的背景.
研究的目的:
- 评估六种空气污染物与兰州每日AR门诊访问之间的关联.
- 分析滞后效应并确定易受影响的子组 (性别,年龄,季节).
- 提供关于空气质量和AR的公共卫生干预措施的证据.
主要方法:
- 用分布式滞后非线性模型 (DLNM) 进行准森时间序列回归.
- 分析2014-2019年每天对AR和6种空气污染物 (PM2.5,PM10,SO2,NO2,O38h,CO) 的门诊诊次数.
- 按性别,年龄和季节进行分层分析.
主要成果:
- 在所有六种空气污染物之间发现了显著的关联,并增加了AR门诊访问.
- 观察到的最强的关联是每个污染物的特定滞后日 (例如,PM2.5在0-7天).
- 男人和成年人 (15-59岁) 显示出更高的敏感性;影响因季节而异.
结论:
- 对PM2.5,PM10,SO2,NO2,O38h和CO的短期暴露与AR门诊访问的增加有显著的相关性.
- 污染物的影响因性别,年龄组和季节而异.
- 调查结果强调了空气污染对兰州过敏鼻炎的公共卫生影响.
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