三糖糖体质指数和伊朗成年人的高血压风险:基于人口的研究
Hamid Reza Nikbakht1, Farid Najafi2, Ebrahim Shakiba3
1School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
BMC endocrine disorders
|July 21, 2023
概括
三甘油-葡萄糖体重指数 (TyG-BMI) 与伊朗成年人高血压风险较高有关. 这一指数可能有助于通过改变生活方式来早期诊断和预防高血压.
科学领域:
- 心脏病学 心脏病学
- 代谢综合征是代谢综合征的一种.
- 公共卫生 公共卫生
背景情况:
- 胰岛素抵抗 (IR) 和肥胖已成为高血压风险因素.
- 甘油三糖指数 (TyG) 作为IR的替代标志物.
- 三甘油-葡萄糖体重指数 (TyG-BMI) 是一种结合TyG和BMI的新型指数.
研究的目的:
- 调查TyG-BMI指数与高血压风险之间的关联.
- 评估TyG-BMI作为伊朗成年人高血压的潜在早期诊断标志物.
主要方法:
- 这是一项对来自拉凡萨尔非传染性疾病 (RaNCD) 队列的8610名伊朗成年人进行的横截面研究.
- 后勤回归分析,以评估TyG-BMI和高血压之间的关系.
- 接收机操作特征 (ROC) 曲线分析,以确定TyG-BMI的预测能力.
主要成果:
- 高血压患者与正常血压患者相比,具有显著更高的人类指数.
- 与最低四分位数相比,TyG-BMI的最高四分位数显示高血压的几率增加了3.10倍.
- TyG-BMI显示高血压的预测能力为61% (AUC:0.61),单独超过BMI和TyG.
结论:
- TyG-BMI指数与高血压增加的可能性有显著的关联.
- TyG-BMI可以作为一种有价值的临床工具,用于早期发现高血压.
- 改变生活方式,包括通过体力活动和饮食来控制体重,对于改善IR和预防高血压至关重要.
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