对于不可治愈的晚期胃癌,在息手术中需要进行阴道切除吗? :一个追溯的病例控制研究
1Department of Surgery, Yeungnam University Medical Center, 170 Hyeonchungno, Nam-Gu, Daegu, 42415, Korea. cjschddnsrja@gmail.com.
World journal of surgical oncology
|July 21, 2023
概括
吸管切除术 (vagotomy) 是一种涉及对交感神经切除的手术,当与息性胃结节术 (PGJ) 结合时,可局部切除的胃癌 (LUGC) 患者的存活率显著提高. 这种方法提供了低并发症风险的生存益处.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 神经系统影响胃癌的发病和进展.
- 交感神经可能会抑制,而副交感神经可能会促进胃癌的生长.
- 消化器切除切除了刺激胃的副交感神经.
研究的目的:
- 为了研究阴道切除术对胃癌进展的影响.
- 为了比较缓解性胃肠静脉切除术 (PGJ) 与PGJ与阴道切除术 (PGJV) 的预后.
主要方法:
- 由于晚期胃癌而导致胃出口阻塞的患者的回顾性审查.
- 患者接受了PGJ或PGJV.
- 分析局部不可切除的胃癌 (LUGC) 和患有远程转移的胃癌 (GCDM) 的组的整体存活率 (OS).
主要成果:
- 在PGJ和PGJV之间,手术结果或并发症没有显著差异.
- 在GCDM组中,吸血术并不是OS的重要因素.
- 在LUGC组中,Vagotomy显著改善了OS,特别是在多变量分析中与PGJ结合时.
结论:
- 用PGJ为LUGC进行阴道切除术提供了额外的生存益处,并发症风险较低.
- 需要进一步的前性研究,采用大样本大小,以确认vagotomy对胃癌生长的影响.
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