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在关节痛患者中,C型肝炎病毒的患病率:是否有逻辑进行查?
Arwa Mohammed Othman1, Asma'a Ahmed Al-Hnhna2, Belques Sharaf Al-Huraibi3
1Microbiology and Immunology Department, Faculty of Medicine and Health Sciences, Sana'a University, Sana'a, Yemen. arwaothman@hotmail.com.
Virology journal
|July 21, 2023
概括
肝炎C病毒 (HCV) 与关节疼痛有关. 这项研究发现,慢性关节痛患者中,特别是男性中,HCV患病率为4.8%,建议对早期检测进行查.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 类风湿病学 类风湿病学
- 传染性疾病 传染性疾病
背景情况:
- 肝炎C病毒 (HCV) 与肝外表现有关,包括诸如关节痛等类风湿病.
- 之前的研究表明,HCV感染个体的风湿病症状的频率很高.
- 无法解释的关节痛可能是沉默的HCV感染的早期指标.
研究的目的:
- 为了确定肝炎C病毒 (HCV) 在慢性不明原因关节痛患者中的患病率.
- 为了促进早期检测和治疗潜在的沉默HCV感染.
- 为了研究HCV和类风湿症状之间的关联.
主要方法:
- 进行了一项横截面观察性研究,包括145名患有慢性不明原因关节痛的患者.
- 血清样本使用免疫染色学试验测试了抗HCV抗体.
- 聚合酶链反应 (PCR) 用于检测HCVRNA在阳性血清样本中进行确认.
主要成果:
- 观察到抗HCV抗体的血清流行率为4.8% (7/145),HCVRNA的分子流行率为3.4% (5/145).
- 与女性相比,HCV感染在男性患者 (11.9%) 中明显更为普遍.
- 在HCV感染和年龄,输血史,手术,个人剃须工具使用或医疗保健工作者身份之间没有发现显著的关联.
结论:
- 肝炎C病毒 (HCV) 患病率在患有关节痛的男性中特别高.
- 建议对患有关节痛的患者,特别是男性进行HCV查,以实现早期诊断.
- 这种方法可以帮助识别和管理带有关节疼痛的无声HCV感染.
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