在英国一家三级医院内采用生物类似药物的有效性:6年随访
Andrew Barron1, Jennifer Chung1, Robin E Ferner1,2,3
1University College London Hospitals NHS Foundation Trust, London, UK.
British journal of clinical pharmacology
|July 21, 2023
概括
这项研究展示了一个医院的医院.
科学领域:
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
- 临床药房 临床药房 临床药房
背景情况:
- 与原始生物制品相比,生物类似药可节省成本.
- 有效的生物类似药的采用对于医疗系统的节约至关重要.
- 评估切换后的患者结果和潜在的逆转是很重要的.
研究的目的:
- 描述一家医院的生物类似药采用策略.
- 将这一战略的效率与全国平均水平进行比较.
- 评估患者在转换后恢复原始生物制剂的益处.
主要方法:
- 描述了一个单一的医院信托的生物类似物采用过程.
- 将采用速度和完整性与英语国家数据进行比较.
- 随访了那些重新使用原始生物药物的患者.
主要成果:
- 描述的方法导致了更快,更完整的生物类似药的采用.
- 这导致2021/2022年额外节省38万英.
- 87%的恢复原始生物药物的患者显示短期改善,长期保留好处.
结论:
- 医院的生物类似药采用策略表现优于英国的平均水平.
- 该策略允许患者在临床上适当的情况下恢复原始生物制剂.
- 这种方法提高了成本效益,同时保持了患者的福祉.
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