多药性是否与在家生活的85岁以上的人难以服用药物有关? 来自纽卡斯尔85+研究的发现
Laurie E Davies1, Adam Todd2, David R Sinclair1
1Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
多药性 (服用多种药物) 与在家生活的老年人服用药物的困难无关. 相反,残疾和损伤预测了这些挑战,需要有针对性的支持.
科学领域:
- 老年学是一门学科.
- 药学流行病学 药学流行病学
- 老年医学 老年医学
背景情况:
- 多药在老年人中很常见,但其与独立生活者服用药物的困难的关联尚不清楚.
- 家庭护理人员的可用性下降可能会影响老年人对药物的坚持.
- 了解影响药物坚持的因素对于保持晚年独立生活至关重要.
研究的目的:
- 调查85岁及以上社区居民多药店与药物服用困难之间的关联.
- 在这个人口群体中确定药物服用困难的预测因素.
主要方法:
- 利用了来自纽卡斯尔85+研究的数据,这是一项纵向队列研究.
- 雇员混合效应建模,分析多药 (连续和分类) 与自我报告的药物服用困难之间的关系.
- 评估了潜在的混因素的影响,包括残疾,视力障碍和认知障碍.
主要成果:
- 多药性,无论是连续测量还是分类测量 (5-9或≥10种药物),与服用药物的困难没有显著关联.
- 障碍,视力障碍和认知障碍被确定为难以服用药物的重要预测因素.
- 这些障碍预测困难,无论处方药的数量如何.
结论:
- 在85岁以上的社区居民中,服用药物的困难主要与功能和认知障碍有关,而不是药物的数量.
- 医疗保健专业人员应主动评估和解决残疾,视力或认知障碍的老年人药物管理方面的挑战.
- 干预措施应侧重于潜在的障碍,而不仅仅是减少服用药物的负担,以支持药物坚持.
更多相关视频
12:18A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
04:13Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults
Published on: February 8, 2019
相关概念视频
Drug Therapy
Antianxiety Medications
Factors Affecting Drug Response: Overview
Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance
A study on guinea pigs examined the...
Documentation in Long-Term and Home Healthcare Setting
Long-Term Care Facilities
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Dosage Regimen: Overview
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
