蛋白质丧失肠病症的狗的营养不良查得分:一个前性的多中心研究
Florence E Wootton1, Christopher S F K Hoey2, Glynn Woods3
1Department of Clinical Science and Services, Royal Veterinary College, Hatfield, UK.
Journal of veterinary internal medicine
|July 22, 2023
概括
一个新的营养不良查分数 (USS) 对患有蛋白质丧失肠病 (PLE) 的狗可以预测结果. 狗不达到缓解的最重要的指标是轴肌肉损失和外套状况.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 狗胃肠病学 狗胃肠病学
- 临床营养学 临床营养学
背景情况:
- 狗的蛋白质丧失肠病 (PLE) 可能导致营养不良,但其影响和预测结果的因素尚不清楚.
- 确定预测结果的预测因素对于管理患有PLE的狗至关重要.
研究的目的:
- 为诊断出PLE的狗制定营养不良查得分 (USS).
- 评估USS对患有PLE的狗的临床结果的预测价值.
主要方法:
- 一项前性研究涉及来自英国三家转诊医院的57只患有PLE的狗.
- 根据食欲,体重减轻,身体状况,肌肉状况和外套状况开发了一个USS,得分为15分.
- 在诊断后,对狗进行了至少六个月的随访.
主要成果:
- 在六个月内未能达到临床缓解的狗在诊断时的USS显著更高,与缓解的狗相比.
- 整体USS显示中度预测能力 (AUC 0.656) 没有缓解.
- 一个简化得分仅使用轴肌损失和外套状况显示出优异的预测值 (AUC 0.728).
结论:
- 圆轴肌肉损失和外套状况是识别PLE不太可能在六个月内实现临床缓解的狗的最有预测力的变量.
- 这些发现表明,简化肌肉和外套状况的评估可以帮助预测患有PLE的狗的结果.
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