运动诱导的心肌T1增加和娱乐骑自行车的人的右心室功能障碍:一个CMR研究
Olivier Ghekiere1,2, Lieven Herbots3,4, Benjamin Peters3,5
1Faculty of Medicine and Life Sciences/LCRC (-MHU), Hasselt University, Agoralaan, 3590, Diepenbeek, Belgium. olivier.ghekiere@jessazh.be.
European journal of applied physiology
|July 22, 2023
概括
骑自行车的人的强度运动会增加心脏素I (cTnI) 和T1放松时间,表明心肌变化. 这些变化与右心室功能障碍相关,突出显示了耐力赛事对心脏健康的潜在影响.
科学领域:
- 心脏病学 心脏病学
- 运动医学 运动医学
- 生物标志物 生物标志物
背景情况:
- 剧烈的运动可以提高心脏 I (cTnI),但运动诱导的心肌并未得到充分理解.
- 心脏磁共振 (CMR) 原生T1/T2映射可以检测心肌水含量增加.
研究的目的:
- 用生物标志物,心声学和CMR来评估休骑自行车者的急性心肌变化,在使用艰苦运动后.
- 为了评估心肌T1和T2放松时间的运动诱导变化.
主要方法:
- 19名男子休骑自行车者完成了一场175公里长的自行车比赛.
- 心脏磁共振 (CMR) 和心声扫描在运动前和运动后进行.
- 采集血液样本以测量心脏生物标志物,如cTnI.
主要成果:
- 运动后,cTnI和T1放松时间显著增加 (p < 0.001).
- 赛后发现右心室 (RV) 功能障碍和减少RV应变 (p < 0.05).
- 增加的T1放松时间与cTnI释放,RV功能障碍以及在高心率区域度过的时间相关.
结论:
- 在休骑自行车运动员中,艰苦的运动会导致比赛后早期的cTnI增加,T1放松时间增加和RV功能障碍.
- 这些运动引起的心脏变化是相互依存的.
- 这些发现的长期临床意义需要进一步调查.
相关概念视频
Imaging Studies for Cardiovascular System IV: CMRI
64
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
64
Cardiomyopathy IV: Restrictive Cardiomyopathy
12
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
12
Cardiomyopathy III: Hypertrophic Cardiomyopathy
16
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
16
Exercise and Cardiovascular Response
866
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
866
Myocarditis I: Introduction
10
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
10


