与刺激引起的发作相关的因素以及与外科手术结果的相关性
Xue-Min Zhao1, Hui-Juan Wan2, Xiao-Qiu Shao3
1Department of Neurophysiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Clinical neurology and neurosurgery
|July 22, 2023
概括
电刺激映射 (ESM) 有助于识别发作发作区域. 特定的发作发作模式和II型的焦点皮层发育不良症预测刺激诱导的发作,而先前的手术可能会降低发作可能性. 这些因素也会影响外科手术的结果.
科学领域:
- 发病学 (Epileptology) 是一个专业的学科.
- 神经外科 神经外科
- 神经生理学 神经生理学
背景情况:
- 带有电刺激映射 (ESM) 的立体电脑电图 (SEEG) 对于在中定位发区域至关重要.
- 了解影响刺激发作 (SIS) 的因素及其对外科手术结果的影响,对于患者管理至关重要.
研究的目的:
- 在ESM期间识别与刺激诱导 (SIS) 相关的因素.
- 确定在接受ESM的患者中有利的外科结果的预测因素.
主要方法:
- 对80名患者进行SEEG与常规ESM的分析.
- 将患者分为SIS-阳性 (SIS-P) 和SIS-阴性 (SIS-N) 的组.
- 在接受了彻底手术的患者中,对手术结果 (Engel I vs. Engel II-IV) 的评估.
主要成果:
- 在LVFA (PRED→LVFA) 和焦点皮层发育不良 (FCD) 后,先前的重复性发泄的发作发作模式 (SOP) 和II型焦点皮层发育不良 (FCD) 是SIS的独立预测因素.
- PRED→LVFA SOP和SIS预测了有利的外科手术结果,而双边电极植入预测了不利的结果.
- 之前的手术显示了与SIS和良好的外科治疗结果的负面关联.
结论:
- 对于发作区域定位而言,ESM非常有价值.
- PRED→LVFA SOP和FCD类型II与引发SIS相关.
- 特定的标准操作程序和SIS的存在预测了手术的成功,而双边植入表明了较差的结果.
更多相关视频
相关概念视频
Epilepsy and Seizures: Overview
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Seizures l: Introduction
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...


