细菌,真菌和植物中的核糖体失活蛋白的进化和自然选择
Jian Liu1, Daxing Wen2, Xianliang Song2
1State Key Laboratory of Crop Biology, Agronomy College, Shandong Agricultural University, Tai'an, Shandong Province 271018, PR China; ShanghaiMunicipal Agricultural Technology Extension & service Center, Shanghai 201103, PR China.
International journal of biological macromolecules
|July 22, 2023
概括
这项研究在细菌,真菌和植物中确定了1592个核糖体失活蛋白 (RIP) 基因. 植物RIP,特别是在非种子植物中缺席,显示出明显的进化模式,可能与种子生存有关.
科学领域:
- 分子生物学分子生物学
- 进化生物学 进化生物学
- 生物化学 生物化学
背景情况:
- 核糖体失活蛋白 (RIPs) 赋予各种生物耐药性,包括抗真菌,抗病毒,抗昆虫和抗瘤性质.
- RIP被分为主动细菌/真菌类型和被动植物类型,反映了不同的防御机制.
研究的目的:
- 在细菌,真菌和植物中识别和表征核糖体失活蛋白 (RIP) 基因.
- 调查RIP的进化起源和多样化,特别是在植物王国.
主要方法:
- 对基因组数据的生物信息分析以识别RIP基因.
- 在不同种群中对RIP基因分布和特征进行比较分析.
- 遗传学分析以推断RIP基因的进化关系和起源.
主要成果:
- 在细菌,真菌和植物中共发现了1592个RIP基因.
- 细菌RIP主要是Shiga或Shiga类毒素 (88%),而真菌RIP主要是分泌的蛋白质 (98%).
- 在非种子植物中缺少RIP,但在种子植物中存在,在二和单之间观察到进化分歧;RIP2基因似乎是古老的和植物特异的,RIP1可能从RIP2演变为RIP1.
结论:
- RIP的分布和演变在不同王国之间有很大差异,植物具有独特的特征,可能与生殖结构有关.
- RIP2基因可能代表了早期的植物特异性创新,随后的进化可能导致RIP1基因.
- 这项研究为核糖体失活蛋白的进化轨迹提供了新的视角.
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