在怀疑阻塞性睡眠呼吸暂停时,外围动脉度测量与多睡眠学相比
Jonathan Röcken1, Desiree M Schumann1, Matthias J Herrmann1
1Clinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital of Basel, Basel, Switzerland.
European journal of medical research
|July 22, 2023
概括
周围动脉度测量 (PAT) 与多睡眠法 (PSG) 在诊断阻塞性睡眠呼吸暂停 (OSA) 方面有很好的一致性,特别是在中度至严重的病例中. 患有不一致或一致的OSA诊断的患者之间,心血管风险类似.
科学领域:
- 睡眠医学 睡眠医学
- 心血管健康 心血管健康
- 诊断的准确性 诊断的准确性
背景情况:
- 多睡眠学 (PSG) 是诊断阻塞性睡眠呼吸暂停 (OSA) 的黄金标准.
- 使用外周动脉度计 (PAT) 进行家庭睡眠呼吸暂停测试是患有OSA风险增加的患者推的替代方案.
- 调查PAT和PSG之间的一致性对于理解诊断准确性和患者结果至关重要.
研究的目的:
- 评估PAT和PSG在诊断OSA中的一致性.
- 为了确定PAT和PSG之间不一致的OSA诊断的预测因素.
- 为了评估与匹配的一致患者相比,与不一致的OSA诊断患者的三年心血管风险.
主要方法:
- 一项回顾性单心队列研究包括940名患者,PAT呼吸暂停-呼吸暂停指数 (AHI) ≥5/h,随后在三个月内住院治疗PSG.
- 患者被分为不一致的 (PAT AHI ≥ 5/h,PSG AHI < 5/h) 或一致的 (PAT AHI ≥ 5/h,PSG AHI ≥ 5/h).
- 主要不良心血管事件 (MACE) 在不一致的患者和匹配的一致的患者中被分析了3.1年.
主要成果:
- 在PAT和PSG之间OSA诊断的总体一致性为80% (55%轻度,86%中度/重度OSA).
- 不一致的诊断与女性性别,年龄较小和BMI较低有关,但与并发症无关.
- 不一致 (n=155) 和匹配一致 (n=274) 患者之间没有观察到MACE的显著差异.
结论:
- 在OSA诊断方面,PAT与PSG具有很好的一致性,特别是在中度和重度OSA.
- 年龄,性别和BMI是PAT和PSG之间不一致的OSA诊断的重要预测因素.
- 重大心血管不良事件的风险是相似的,无论OSA是通过PAT或PSG诊断.
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