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Updated: Jul 22, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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皮林变体E148Q增强了炎症酶激活和cis中的致病突变的影响

Thomas Reygaerts1,2, Pawat Laohamonthonkul1,2, Katja Hrovat-Schaale1,2

  • 1Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

Rheumatology (Oxford, England)
|July 23, 2023
PubMed
概括

皮林的p.E148Q变体增强了炎症酶的激活,导致家族地中海热 (FMF) 等自身炎症性疾病. 这个变种这种变种.

关键词:
FMF FMF FMF 的意思是什么意思一个IL-1的IL-1.细胞因子 细胞因子一些炎症一些炎症多形态主义的多态主义.皮林 (pyrin) 是一种素.风险因素的风险因素是什么

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