表表转录体在塑造植物应激反应中的新兴作用
Yashika Dhingra1, Shitij Gupta1,2, Vaishali Gupta1
1Department of Plant Molecular Biology, University of Delhi South Campus, New Delhi, 110021, India.
Plant cell reports
|July 23, 2023
概括
植物表写体,包括RNA修改和编辑,对于发育和应激反应至关重要. 了解这些过程可以帮助设计作物,以改善应激耐受性,以应对全球气候变化挑战.
科学领域:
- 分子生物学分子生物学
- 植物科学 植物科学
- 遗传学 是一个遗传学.
背景情况:
- 表写体,包括RNA修改和编辑,在基因调节中发挥着关键作用.
- 存在超过170种RNA修饰,其中N6-甲基氨酸 (m6A),伪尿氨酸 (Ψ) 和细胞氨酸甲基化 (m5C) 是丰富的.
- 这些修改增加了一层基因调节层,影响RNA属性和细胞信息.
研究的目的:
- 审查当前对植物应激反应中的RNA修饰和编辑的理解.
- 突出表转录组探索的潜力,以设计抗压作物.
主要方法:
- 高通量测序以分析压力下表表体转录组动态.
- 基因实体学 (GO) 分析以确定与RNA修饰相关的与压力相关的途径.
- 对RNA修饰机械 (写字器,读字器,擦拭器) 的基因表达模式的分析.
主要成果:
- 在植物压力条件下,RNA修饰和编辑景观是动态的.
- 像m6A,m5C和 Ψ这样的特定修饰在应激响应的转录中得到丰富.
- 参与RNA修饰机制的基因的改变表达会影响植物的应激耐受性.
结论:
- 表表写体对植物发育和应激适应至关重要.
- 准RNA编辑机械可以提高作物应激耐受性.
- 对表观转录组的进一步研究为开发适应气候变化的作物提供了途径.
相关概念视频
Transcription
147.3K
Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
147.3K
Responses to Heat and Cold Stress
13.6K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
13.6K
Responses to Salt Stress
13.2K
Salt stress—which can be triggered by high salt concentrations in a plant’s environment—can significantly affect plant growth and crop production by influencing photosynthesis and the absorption of water and nutrients.
13.2K
Riboswitches
8.2K
Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
8.2K
Cell Signaling in Plants
5.7K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
5.7K
Other Stress Responses in Bacteria
33
Bacteria have global regulatory systems that control several types of stress mechanisms. These include Pho regulon and the heat shock response, which are essential systems for environmental adaptation, such as nutrient limitation and proteotoxic stress. The Pho regulon and the heat shock response exemplify bacterial resilience, enabling rapid adaptation to fluctuating environmental conditions.Pho RegulonBacteria require phosphorus for essential cellular processes, including nucleic acid...
33


