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人类IP3受体三重淘汰干细胞尽管改变了线粒体代谢,但仍然具有多能性

Julius Rönkkö1, Yago Rodriguez1, Tiina Rasila1

  • 1Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, 00290, Finland.

Cell calcium
|July 23, 2023
PubMed
概括

伊诺西1,4,5-三酸盐受体 (IP3R) 对于细胞信号传递至关重要. 在人类诱导多能干细胞 (hiPSCs) 中淘汰所有IP3R异构体并没有影响多能性,但改变了线粒体代谢.

关键词:
在Ca2+) 信号传输中.IP(3) R1 一个R1一个IP(3) R2 2 的时间.IP ((3) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33) R33)诱导的多能干细胞干细胞伊诺西1,4,5-三酸盐受体的受体线粒体中的线粒体.在TCA,TCA,TCA中使用.这就是 iPSC 的意义.

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