在不同表面热源下的温度依赖的导热率和新陈代谢的烧伤数值模拟
Faishal Ansari1, Rajneesh Kumar Chaudhary1, Jitendra Singh1
1Department of Mathematics, Institute of Science, Banaras Hindu University, Varanasi, 221005, India.
Journal of thermal biology
|July 23, 2023
概括
这项研究使用非线性生物热模型在前臂组织中模拟热传输. 研究结果表明,调整血液 perfusion 和热量流可以管理烧伤和达到高温.
科学领域:
- 生物医学工程 生物医学工程
- 热传递热量转移的方法
- 计算生物学 计算生物学
背景情况:
- 了解人体组织中的热传输对于预测烧伤的伤害至关重要.
- 前臂组织特性,包括温度依赖的导热率和代谢热量,影响温度分布.
- 烧伤受到受伤组织层厚度的显著影响.
研究的目的:
- 用一维非线性生物热传递模型研究人类前臂组织内的热传递现象.
- 为了预测温度分布,考虑到温度依赖的导热率和代谢热量.
- 分析内部组织和骨的温度分布,以了解烧伤机制.
主要方法:
- 采用了一维非线性生物热传递模型.
- 用有限差异和bvp4c数值技术进行温度分布分析.
- 数字代码的准确性与精确的分析结果以及混合的Runge-Kutta/有限差异方案进行了验证.
主要成果:
- 均的热流会影响外皮温度,而阴侧热流会影响皮下和内组织温度.
- 在44°C的热源下没有观察到烧伤伤害,但在更高的温度下可能会发生.
- 增加血液输液和减少代谢热量,热导率和热流可以减轻烧伤的伤害.
结论:
- 开发的数值模型准确地预测了前臂组织中的温度分布.
- 管理血液 perfusion 和热流参数是防止烧伤和诱导高温症的关键.
- 该研究提供了关于前臂组织热管理策略的见解.
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