梅毒自我检测作为关键人群中额外的梅毒检测方法的作用:系统性审查和元分析
Janet M Towns1, Warittha Tieosapjaroen1, Maeve B Mello2
1Melbourne Sexual Health Centre, Alfred Health, Melbourne, VIC, Australia; Central Clinical School, Monash University, Clayton, VIC, Australia.
The Lancet. Public health
|July 23, 2023
概括
梅毒自我测试 (SST) 是可行的和可以接受的,88%的用户完成了测试. 需要进一步的研究来确定最佳实施的敏感性和特异性.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 诊断测试 诊断测试 诊断测试
背景情况:
- 梅毒疫情需要创新的测试策略.
- 梅毒自我检测 (SST) 显示出增加检测和治疗覆盖率的希望.
- 关于SST实用性的证据综合对于公共卫生干预至关重要.
研究的目的:
- 系统地审查和综合有关梅毒自我测试 (SST) 实用性的现有证据.
- 评估SST作为梅毒检测方法的可行性和可接受性.
- 识别有关SST性能特征的文献上的差距.
主要方法:
- 从2000年到2022年对出版物的系统审查和元分析.
- 搜索了多个数据库,包括MEDLINE,Embase,CINAHL,Scopus和科学网络.
- 包括使用梅毒快速测试原始数据的研究,包括双HIV-SST,没有人口限制.
主要成果:
- 来自七项研究的11篇论文符合资格标准;四篇论文重点关注与男性发生性关系的男性.
- 在提供套件后进行SST的个人总比重为88% (95%CI 85-91).
- 报告称,由于方便,隐私和快速结果,用户和提供商对SST的偏好很高;然而,没有发现敏感性或特异性的数据.
结论:
- 公共安全技术是可以接受和可行的,有潜力接触到服务不足的人群.
- SST可以作为一种额外的梅毒检测方法.
- 需要进一步的实施研究来优化SST服务交付和扩展.
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