穿皮电针刺激与德克萨米他用于预防术后恶心和吐在乳腺手术:一个非劣势的随机对照试验
Yongyan Zhang1, Ying Li1, Feng Ji1
1Department of Anesthesiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, China.
Surgery
|July 23, 2023
概括
经皮电针刺激 (TEAS) 在预防经过乳房手术后的术后恶心和吐方面与甲基一样有效. 使用TEAS的患者报告了更高的满意度,表明其可行性和有效性.
科学领域:
- 麻醉学和疼痛管理
- 手术瘤学手术瘤学
- 综合医学是一个整体的医学.
背景情况:
- 手术后恶心和/或吐 (PONV) 是手术后的一个常见并发症.
- 德克萨米他是PONV的标准药理干预措施.
- 非药理学方法,如穿皮电针点刺激 (TEAS) 提供了另一种方法.
研究的目的:
- 为了比较Neiguan acupoint (PC6) 的非劣势性,TEAS与德克萨米他对抗PONV.
- 评估PC6 TEAS的患者满意度和可行性,以预防女性乳腺手术患者的PONV.
主要方法:
- 一项非劣等性随机研究,涉及280名接受乳腺手术的女性患者.
- 两个组:PC6 TEAS (n=140) 和德克萨米他8毫克静脉注射 (n=140).
- 术前和术后给予TEAS; 在麻醉诱导之前给予德克萨米他. 在手术后24小时评估结果.
主要成果:
- 在降低PONV发病率方面,TEAS与德克萨梅他无差 (31.1%与27.9%的协议).
- 在TEAS组中,患者满意度得分显著更高 (3.9对3.6,P=.003).
- 发现PC6患者控制的TEAS是一种可行的PONV预防方法.
结论:
- PC6 TEAS是一种非劣质的替代剂,用于预防乳腺手术后24小时内PONV.
- 在Neiguan针点进行患者控制的TEAS是可行的,并且与患者满意度的提高有关.
相关概念视频
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
249
5-HT3 receptor antagonists, such as dolasetron, granisetron (Kytril), ondansetron (Zofran), and palonosetron (Axoli), are crucial in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea. These drugs selectively block 5-HT3 receptors in the visceral vagal and spinal afferent nerves, chemoreceptor trigger zone, and the vomiting center. They have a rapid onset of action and can be given as a single dose before chemotherapy. Ondansetron and granisetron, in particular,...
249
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
202
Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy. SP binds and activates...
202


