谷物消费对心脏代谢风险因素的影响:系统审查和元分析
Ruiting Zhu1, Haiyan Xu1, Hongwei Cai2
1School of Nursing, Jilin University, Changchun, Jilin, 130021, China.
概括
在患有心脏代谢风险因素的人群中,食用谷物有效降低血压,总胆固醇,LDL胆固醇和禁食血糖. 麦在这些条件下表现出最显著的好处.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 心血管疾病 (CVD) 是全球主要的健康问题.
- 心脏代谢风险因素 (CMRFs) 包括高脂血症,高血压,糖尿病和肥胖.
- 饮食干预措施,特别是谷物消费,对于管理CMRF至关重要,尽管结果各不相同.
研究的目的:
- 调查谷物消费对心脏代谢风险因素 (CMRFs) 的影响.
- 对谷物和CMRF进行随机对照试验的综合证据.
主要方法:
- 在主要数据库 (PubMed,Embase,Scopus,Cochrane,Web of Science) 进行了系统的搜索,直到2023年2月.
- 使用随机效应模型对22项符合条件的随机对照研究的数据进行了元分析.
- 效果大小是以加权平均差异 (WMD) 计算的,其中 95% 的置信区间 (CI).
主要成果:
- 谷物的消费显著降低了缩血压 (WMD: -1.59; 95% CI: -2.45至 -0.72) 和腹缩血压 (WMD: -1.96; 95% CI: -3.89至 -0.04).
- 它还降低了总胆固醇 (WMD: -0.19; 95% CI: -0.34至 -0.04),低密度脂蛋白胆固醇 (WMD: -0.21; 95% CI: -0.38至 -0.04),以及禁食血糖 (WMD: -0.13; 95% CI: -0.24至 -0.01).
- 没有观察到对高密度脂蛋白胆固醇,甘油三,腰围或体重指数的显著影响. 麦特别改善了相关患者群体的血脂和血压.
结论:
- 谷物消费显著改善了关键的心脏代谢风险因素,包括血压,总胆固醇,LDL胆固醇和禁食血糖.
- 在不同谷物行业中,麦显示出最明显的有益影响.
- 这些发现凸显了谷物在治疗心脏代谢疾病方面的治疗潜力.
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