人类影响的饮食会影响野生的肠道微生物群
Madelyn Moy1, Laura Diakiw2, Katherine R Amato3
1Department of Anthropology, Northwestern University, Evanston, IL, 60208, USA.
Scientific reports
|July 23, 2023
概括
西方高加工食品饮食显著改变野生的肠道微生物群,减少微生物多样性和有益的纤维降解细菌. 对于显著的微生物组影响,需要最低的饮食变化值.
科学领域:
- 微生物组研究的研究.
- 灵长类动物生态学
- 营养科学 营养科学
背景情况:
- 工业化饮食影响肠道微生物群,影响健康.
- 研究饮食与微生物组的联系在人类和实验室动物中具有挑战性.
- 野生橄 (Papio anubis) 提供了一个可比的模型,因为它们具有相似的微生物组和共同的环境.
研究的目的:
- 为了研究人类改变饮食对野生肠道微生物群的影响.
- 为了比较与人类垃圾 (加工食品,糖,脂肪) 的不同接触.
- 为了确定饮食诱导的微生物组变化的门.
主要方法:
- 16S rRNA基因扩增序列测序用于分析的便微生物组.
- 在卢旺达阿卡格拉国家公园研究了橄.
- 根据对人类垃圾的访问,这些群体被分类为:无限,有限和无限.
主要成果:
- 没有限制地进入垃圾桶的子显示微生物α多样性减少.
- 纤维降解的种群 (Ruminococcaceae,Prevotellaceae,Lachnospiraceae) 在垃圾处理能力较强的中较少.
- 无法进入垃圾桶的子具有与无法进入垃圾桶的子相似的微生物组,这表明了饮食值.
结论:
- 人类影响的高加工食品,糖和脂肪的饮食可以改变野生的微生物组.
- 需要最低限度的饮食改变才能对肠道微生物群产生重大影响.
- 野生灵长类动物研究补充了人类和实验室动物研究的饮食-微生物群-健康相互作用.
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