在使用新精神活性物质的人群中,类似精神病的经历和同时使用物质
Venla Ellilä1, Jonna Levola2,3, Alexander Denissoff1,4
1Department of Psychiatry, Faculty of Medicine, University of Turku, Turku, Finland.
Substance use & misuse
|July 24, 2023
概括
新型精神活性物质 (NPS) 的使用与类似精神病的经历有关,即使考虑到现有的心理健康状况. 同时使用物质可能会影响这些发现,需要在未来的研究中考虑.
科学领域:
- 精神病学是一个精神病学.
- 成 药物 药物 药物 药物
- 毒理学 毒理学 毒理学
背景情况:
- 新精神活性物质 (NPS) 是新兴的药物,旨在规避现有立法.
- 人们越来越认识到NPS的使用,可能与不良的精神病结果有关.
- 关于NPS使用与精神病类似经历之间的关联的研究是有限的.
研究的目的:
- 调查NPS使用与精神病类经历之间的关联.
- 要确定这种关联是否独立于伴随性精神病的精神病持续存在.
- 为了检查NPS用户之间的并发物质使用模式.
主要方法:
- 在芬兰西南部,对219名参加物质使用服务的个人进行了自愿的匿名调查.
- 收集的数据包括药物使用史,精神病发作的服务利用率和并发性精神病状况.
- 使用Prod问卷 (PROD) 来评估类似精神病的经历.
主要成果:
- 17% (n=38) 的参与者报告使用NPS.
- 在对共变量进行调整后,NPS使用与精神病类经历 (PROD屏幕阳性) 有显著的关联.
- NPS使用与寻求物质诱导精神病发作和多物质使用服务相关.
结论:
- NPS使用独立地与精神病类似的经历有关.
- 同时使用物质是研究NPS影响的重要因素和潜在混因素.
- 未来的研究应该在检查NPS相关结果时仔细考虑多重物质的使用.
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