在模仿急性胰腺炎的情况下,内镜是否是强制性的?
Mohammed Hussien Ahmed1, Mohammed Said Radwan1, Amira Amin Salem Tawoos2
1Department of Hepatology, Gastroenterology and Infectious Disease, Kafrelsheikh University,Egypt.
JPMA. The Journal of the Pakistan Medical Association
|July 24, 2023
概括
胰腺酶对胃痛的轻微升高可能表明胃肠粘膜损伤,表明需要上部内镜检查. 这一发现对于患有腹部不适的患者的差异诊断至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 腹痛是一种常见的抱怨,具有不同的病因.
- 胰腺酶的非特异性升高可能会构成诊断挑战.
- 区分腹痛的原因对于适当的患者管理至关重要.
研究的目的:
- 评估在患有腹部不适的患者中轻度胰腺酶升高的临床效用.
- 探索超胺血症作为胃痛潜在差异诊断的作用.
- 为了研究轻度胰腺酶升高与胃肠粘膜损伤之间的关联.
主要方法:
- 进行了一项涉及270名腹痛患者的横截面研究.
- 患者被分为两组:具有轻度胰腺酶升高 (<3倍) 患者和没有胰腺酶升高的患者.
- 诊断工作包括病史,临床检查,实验室测试,成像和上部内镜.
主要成果:
- 170名患者有轻度胰腺酶升高 (I组),而100名没有 (II组).
- 粉酶,脂酶,肝酶,C-反应蛋白和Helicobacter pylori的显著差异在各组之间被观察到 (p<0.05).
- 两组之间没有发现显著的年龄或性别差异.
结论:
- 在患有腹痛的患者中,胰腺酶的轻度升高 (少于三倍) 是胃肠粘膜损伤的迹象.
- 这些发现凸显了诊断上部内镜在评估这些患者的潜在必要性.
- 超胺血症,即使在轻度水平,也需要进一步调查潜在的胃肠道病理.
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