对于肌肉疾病的成年人输液养的指示:一个范围审查
Marloes Middelink1, Nicol C Voermans2, Baziel G M van Engelen2
1Department of Gastroenterology and Hepatology - Dietetics, Radboud University Medical Center, Nijmegen, The Netherlands.
Journal of neuromuscular diseases
|July 24, 2023
概括
输管养可以改善肌肉疾病患者的营养和生活质量. 关键的征兆包括消化不良和减肥,尽管数据仍然有限,需要进一步研究.
科学领域:
- 神经学 神经学
- 胃肠病学 胃肠病学
- 营养科学 营养科学
背景情况:
- 对于患有肌肉疾病 (MD) 的患者来说,维持充足的营养是很困难的.
- 输液养可以显著改善MD患者的营养状况,功能和生活质量.
- 目前缺乏关于在成年MD患者中启动输管养的指导方针.
研究的目的:
- 审查科学文献关于在患有特定肌肉疾病的成年人中启动输管养的指示.
- 专注于面额头骨骨缩症 (FSHD),包容体肌炎 (IBM),1型肌缩症 (DM1),眼肌缩症 (OPMD) 和先天性肌病.
主要方法:
- 根据PRISMA-ScR指南进行了范围审查.
- 在PubMed,Embase和Cinahl数据库中进行文献搜索,截至2022年4月.
- 关键词包括特定的MD类型,消化不良,肠道营养和营养不良.
主要成果:
- 从1046个独特的文章中,包括了9个案例报告和2个回顾案例系列.
- 输管养的主要适应症是消化不良,营养不良/体重减轻以及与吸入相关的呼吸道感染.
- 穿皮内镜胃口术 (PEG) 是最常见的方法;并发症包括呼吸衰竭和管相关问题.
结论:
- 关于MD中输管养的证据有限.
- 输管养的指示在不同类型的MD中似乎是一致的.
- 在MD管理中推查,渴望和营养不良,并呼吁进行更多的研究.
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