使用潮尾二氧化碳测量的额外死空间对通风早产婴儿的影响:一项实验研究
概括
潮尾CO2测量适度增加了早产婴儿的呼吸力度,影响因流量传感器而异. 封闭式吸气对通风功率的负面影响比二氧化碳监测更大.
科学领域:
- 新生儿重症监护的新生儿重症监护
- 呼吸系统生理学 呼吸系统生理学
- 机械通风机械通风机械通风机
背景情况:
- 呼吸道的死空间增加了通风引起的肺损伤的风险.
- 增加的死空间需要更高的潮体积,对早产婴儿构成风险.
- 潮尾二氧化碳测量插件增加了死空间,并且通常在新生儿中避免使用.
研究的目的:
- 评估终潮二氧化碳测量适配器对早产婴儿通风的影响.
- 量化二氧化碳测量对二氧化碳消除时间的影响.
- 为了比较与二氧化碳监测相关的通风力,与其他通风辅助器相比.
主要方法:
- 一个实验设置,使用二氧化碳淹没的早产婴儿试验肺.
- 结合一个端潮二氧化碳测量适配器与各种气动计程仪 (PNT-A,PNT-B,PNT-Neo) 和一个闭式吸气适配器.
- 在不同的配置下测量二氧化碳消除时间.
主要成果:
- 肺动图显著延长了二氧化碳排放时间,PNT-B显示最大的增加 (32.7%).
- 终潮二氧化碳测量适配器增加了适度的消除时间 (3.1-3.6%),这取决于所使用的气动tachograph.
- 闭合吸收增加了二氧化碳排放时间,与PNT-Neo,PNT-A或PNT-B一起使用时具有显著的影响.
结论:
- 流量传感器对通风力度的影响最大.
- 潮尾二氧化碳测量对通风力有适度的影响,受特定流量传感器的影响.
- 封闭的吸气装置对通风力有较大的负面影响,相比于端潮二氧化碳测量.
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