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在三级医疗机构进行新生儿急诊手术的术后结果-一项前性观察性研究
Sunaakshi Puri1, Indu Mohini Sen1, Neerja Bhardwaj1
1Department of Anaesthesia and Intensive care, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Paediatric anaesthesia
|July 24, 2023
概括
新生儿外科手术死亡率高是发展中国家的一个担忧. 这项研究确定了关键的风险因素,并发现切换到非侵入性通风可以降低手术新生儿的死亡率.
科学领域:
- 新生儿手术 新生儿手术
- 儿科重症监护中心儿童重症监护中心
- 手术结果研究研究.
背景情况:
- 新生儿外科死亡率在发展中国家仍然很高,需要更深入地了解外科手术期间的因素.
- 在外科手术前期优化致病因素对于改善手术新生儿的治疗结果至关重要.
研究的目的:
- 为了评估接受外科手术的新生儿的外科手术过程.
- 确定可能导致这一脆弱人群中术后死亡率的潜在因素.
主要方法:
- 一项前性观察性研究,涉及在三级医疗机构接受紧急手术的新生儿.
- 主要结局:6周术后死亡率. 通过观察和电话跟踪收集的数据.
- 用多变量逻辑回归分析来确定独立的风险因素.
主要成果:
- 招募了278名新生儿;36.2%的新生儿经历了6周死亡率. 常见的诊断包括气管-食道和直肠形.
- 死亡的独立风险因素:早产 (怀孕<34周),术前氧气治疗,术后内托普支持,机械通风和白血病.
- 从侵袭性转换为非侵袭性正压通风,在术后显著降低死亡风险.
结论:
- 早产,手术前的氧气,手术后的内,机械通风和白血病是手术新生儿6周死亡率的重要预测因素.
- 早期过渡到非侵入性正压通风,有望减少新生儿手术死亡率.
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