单侧前庭功能缺陷患者的慢性症状:系统性审查和元分析
Mustafa Karabulut1, Lien Van Laer2, Ann Hallemans2
1Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, Netherlands.
Frontiers in neurology
|July 24, 2023
概括
在大多数患者中,单侧前庭功能缺陷 (UVH) 会导致慢性头和失衡. 静脉干预显著减少残疾,但有些患者需要进一步的治疗策略.
科学领域:
- 垂体神经科学 垂体神经科学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 康复医学 康复医学 康复医学
背景情况:
- 单侧前庭功能缺陷 (UVH) 是一种影响平衡和空间定向的疾病.
- 患有UVH的患者经常报告一系列影响日常生活的慢性症状.
- 了解这些症状的全谱对于有效管理至关重要.
研究的目的:
- 系统地审查和描述UVH患者自我报告的全谱慢性症状.
- 调查各种干预措施在缓解这些症状方面的有效性.
- 确定可能需要替代或补充治疗方法的患者子组.
主要方法:
- 根据PRISMA指南进行了系统审查.
- 在主要数据库 (PubMed,科学网,Embase,Scopus) 进行相关研究的文献搜索.
- 对自我报告问卷数据的元分析,以综合症状严重程度和干预效应.
主要成果:
- 慢性头 (98%) 和失衡 (81%) 是UVH最常见的症状.
- 紫外线高温显著影响生活质量,在头障碍清单 (DHI) 和症状量表 (VSS) 上的中等分数表明了这一点.
- 静脉干预导致自我报告残疾的显著减少 (DHI分数从51.79降至27.39).
- 实质性的小组患者 (≥32%) 继续经历中度残疾,尽管康复.
结论:
- 慢性头和失衡是UVH的标志性症状,需要全面评估.
- 静脉干预为许多人提供了显著的缓解,但一小部分患者仍然具有功能障碍.
- 对于耐火病例,需要对新的干预措施进行进一步的研究,例如振动性反或前庭植入物.
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