由M引起的内心炎. 在一个免疫能力强的患者中,没有潜在的膜异常
Chaoran Li1, Hui Wang1, Jinzhou Zhang2
1Department of Pulmonary and Critic Care Medicine, Hospital of Xi'an International Medical Center, China.
Heliyon
|July 24, 2023
概括
感染性内心炎 (IE) 是由摩根氏菌 (Morganella morganii) 引起的罕见病,特别是在免疫能力强的个体中. 这一案例突显了在没有先前心脏问题的患者中成功地使用抗生素和手术治疗.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 微生物学 微生物学
背景情况:
- 感染性内心炎 (IE) 最常见的是由菌引起的; 阳性细菌是罕见的致病原体.
- 据报道,以前只有一例因摩根氏菌 (Morganella morganii) 引起的IE病例,发生在免疫受损患者身上.
- IE通常与风险因素相关,如静脉注射药物使用,异物物质或先前存在的膜异常.
研究的目的:
- 在一个免疫能力强的患者中报告由摩根氏菌 (Morganella morganii) 引起的IE的独特病例.
- 强调罕见IE病原体的诊断和治疗挑战.
- 强调在复杂的IE案件中及时干预的重要性.
主要方法:
- 一名34岁的免疫能力强的男性出现了复发性发烧和肺炎.
- 诊断的IE与三植被被证实 transthoracic心声学 (TTE).
- 通过血液培养,NGS和植被分析,Morganella morganii被确定为致病原体.
主要成果:
- 患者尽管没有潜在的膜异常,但由于Morganella morganii而发展出IE.
- 通过广泛的抗生素,包括β-乳酸酶抑制和手术干预,成功治疗.
- 在移除植被和修复三管后,患者完全康复.
结论:
- 摩根氏菌 (Morganella morganii) 是极为罕见的IE病因,特别是在没有膜疾病的免疫能力强的个体中.
- 与β-乳糖酶抑制的广泛抗生素的及时施用对于治疗M. morganii诱导的IE与细菌血症至关重要.
- 在没有潜在心脏病的患者中,手术干预对于管理显著植被和复发性感染的IE至关重要.
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