在健康受试者和中风或外周动脉疾病患者之间对称的低频振荡的差异
Yunfei Ma1, Kexin Luo1, Peng Ding1
1School of Information Science and Engineering, Yanshan University, Qinhuangdao, Hebei, 066004, China.
Heliyon
|July 24, 2023
概括
低频振荡 (LFO) 可以区分血管病变. 这些自主生理过程指标显示出在中风或动脉样硬化患者中识别特定的循环损伤的潜力.
科学领域:
- 生理学 生理学 生理学
- 生物标志物 生物标志物
- 医学诊断 医学诊断 医学诊断
背景情况:
- 通过近红外光谱学 (NIRS) 检测到的低频振荡 (LFO) 反映了自主功能.
- 体可能表明循环功能障碍,有助于疾病的检测和监测.
研究的目的:
- 为了研究LFO作为血管输液生物标志物.
- 在临床患者数据中使用LFO区分血管病变的类型和程度.
主要方法:
- 健康对照组,缺血性中风和外周动脉样硬化患者接受了静止状态LFO检测.
- 从耳叶,手指尖和脚收集了LFO.
- 进行了一致性和相位转移分析.
主要成果:
- 一致性和相位转移区分了健康人与中风和动脉样硬化患者.
- 耳叶的相位变化区分轻度和严重的缺血性中风.
- 脚的一致性和相位变化区分轻度和严重的外周动脉样硬化.
- 分类准确度在70%至85%之间.
结论:
- 血管输液管作为有效的血管输液生物标志物.
- 血管外科医生可以区分血管损伤的类型和程度.
- 周围循环损伤提供了有价值的数据来识别周围循环损伤的子组.
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