通过自适应式闭环呼吸节奏控制器共同激活隔膜和外部肋间肌肉
Rabeya Zinnat Adury1,2, Ricardo Siu2,3, Ranu Jung2,4
1Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, United States.
Frontiers in rehabilitation sciences
|July 24, 2023
概括
隔膜和外部肋间肌肉的同时呼吸节奏延迟隔膜疲劳,并使叹息成为可能. 这种联合肌肉刺激提高了呼吸节奏的效率,而不是只有隔膜的节奏.
科学领域:
- 生物医学工程 生物医学工程
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 机械通风是呼吸辅助的标准,但像呼吸节奏等替代方案可以改善生活质量.
- 目前的呼吸节奏通常只针对隔膜,忽视外部肋间肌肉和叹息生成,这些肌肉对于正常呼吸至关重要.
研究的目的:
- 调查是否同时激活隔膜和外部肋间肌肉可以提高呼吸节奏的效率.
- 为了确定联合肌肉刺激是否延迟隔膜疲劳性,并允许生理叹息诱导.
主要方法:
- 一个自适应的,闭环膜节奏系统被扩展到包括外部肋间肌肉激活和叹息生成.
- 一个动物模型被用来比较隔膜单独的节奏与隔膜和外部肋间肌肉刺激的组合.
主要成果:
- 联合肌肉刺激显著降低了隔膜疲劳性,与隔膜单独刺激相比 (p=0.014).
- 这种新的节奏系统成功地使用联合刺激 (p=0.014) 诱导了带有明显更高潮量的叹息.
结论:
- 同时激活多个吸气肌是呼吸节奏的可行策略.
- 这种方法可以减轻腹膜疲劳,促进叹息的产生,可能改善呼吸系统健康结果.
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