在接受肺移植的接受者中评估来自捐赠者的细菌感染
Sibel Doğan Kaya1, Erdal Taşçı1, Kaan Kırali1
1Department of Infectious Diseases and Clinical Microbiology, Koşuyolu High Specialization Training and Research Hospital, Istanbul, Türkiye.
Turk gogus kalp damar cerrahisi dergisi
|July 24, 2023
概括
在接受肺移植的14%患者中,发生了来自捐赠者的细菌感染. 常见的病原体包括Acinetobacter baumannii和Pseudomonas aeruginosa,影响了患者的治疗结果.
科学领域:
- 移植医学 移植医学
- 传染性疾病 传染性疾病
- 细菌学 细菌学是一门学科.
背景情况:
- 肺移植是一种复杂的手术,通常涉及危急病患者.
- 这些患者容易感染,包括从捐赠者传播的感染.
- 了解来自供体的感染对于改善移植结果至关重要.
研究的目的:
- 研究由肺捐赠者传播的细菌感染的原因和后果.
- 为了识别导致捐赠体感染的特定细菌.
- 评估这些感染对肺移植接受者的影响.
主要方法:
- 在2013年1月至2017年12月期间,对71名肺移植接受者的回顾性分析.
- 供体衍生的细菌感染的定义:在具有临床感染证据的供体和受体样本中,相同的细菌和抗生素敏感性.
- 鉴定细菌物种及其抗生素敏感性模式.
主要成果:
- 十名 (14%) 患者被诊断出患有来自供体的细菌感染.
- 确定了主要的病原体:宝曼尼菌 (3) 杆菌 (3), 杆菌 (3), 肺炎菌 (1), 杆菌 (1), 杆菌 (1), 金黄色葡萄球菌 (1).
- 在研究期间,有4名患有供体感染的患者和24名肺移植接受者死亡.
结论:
- 来自捐赠者的细菌感染代表了肺移植的重大并发症.
- 在住院或ICU患者中存在特定的耐药微生物增加了风险.
- 需要进一步的策略来预防和管理来自捐赠者的感染,以提高存活率.
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