在内分泌治疗期间对年轻乳腺癌患者的性功能进行调查:潜伏类分析
Lu Gan1,2, Yi-Ming Miao1, Xiao-Jing Dong1
1Comprehensive Breast Health Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in medicine
|July 24, 2023
概括
接受内分泌治疗的年轻乳腺癌患者表现出多样化的性功能,有些人经历了高功能障碍和低满意度. 诸如AI/OFS治疗,身体形象问题和经济负担等因素增加了这种风险.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
- 性健康 性的健康
背景情况:
- 内分泌疗法是年轻乳腺癌患者的标准治疗方法.
- 性功能障碍是影响生活质量的常见副作用.
- 了解性功能状态对于整体的患者护理至关重要.
研究的目的:
- 调查接受内分泌治疗的年轻乳腺癌患者的性功能状态.
- 识别不同类别的性功能.
- 分析影响这些类别的因素,并开发女性性功能障碍 (FSD) 的预测模型.
主要方法:
- 对189名接受辅助内分泌治疗的年轻乳腺癌患者进行横截面调查.
- 隐性类别分析以使用FSFI措施对性功能进行分类.
- 后勤回归和名谱用于识别高风险的FSD患者.
主要成果:
- 确定了两个患者组:"高功能障碍-低满意度" (69.3%) 和"低功能障碍-高满意度" (30.7%).
- 与高功能障碍相关的因素包括AI + OFS治疗,身体形象不佳,经济负担和性功能恢复延迟.
- 在预测FSD时,Nomogram的C指数为0.782,达到0.782.
结论:
- 在接受内分泌治疗的年轻乳腺癌患者中,性功能状态异质.
- 识别出高风险因素可以帮助早期检测和干预FSD.
- 诺米图为预后评估和个性化护理提供了一个工具.
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