臭氧疗法作为一种新型的补充治疗方法,用于耐火性异常病 granulomatous 乳腺炎
Neslihan Cabioglu1, Didem Can Trabulus2, Selman Emiroglu1
1Istanbul Faculty of Medicine, Department of Surgery, Istanbul University, Istanbul, Türkiye.
Frontiers in medicine
|July 24, 2023
概括
臭氧治疗 (OT) 显著改善了耐火性异常性粒状乳腺炎 (IGM) 的治疗结果,增加了完整反应率并减少了类固醇依赖. 这种安全有效的补充疗法为IGM患者提供了一个有前途的新选择.
科学领域:
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
- 皮肤病学 皮肤病学
背景情况:
- 异常性颗粒性乳腺炎 (IGM) 可能涉及自身免疫过程.
- 臭氧疗法 (OT) 在风湿病症中表现有前途.
- 在耐火性IGM中OT的有效性需要研究.
研究的目的:
- 评估臭氧治疗 (OT) 对耐火性异常性颗粒性乳腺炎 (IGM) 患者的临床有效性.
- 为了比较标准类固醇治疗 (ST) 与ST结合全身OT的结果.
主要方法:
- 一项队列研究包括47名经过活检验证的IGM和对ST的不完全反应的患者.
- 队列A (n=23) 接受了进一步的ST;队列B (n=24) 通过自血疗法 (AHT) 接受了ST加全身OT.
- 在为期四个月的OT治疗期和12个月的中位数随访期后评估了结果.
主要成果:
- 队列B显示显著更高的完全响应率 (37.5%对0%;p=0.002).
- 在OT组中,一年内复发率较低 (21%对70%;p=0.001).
- OT显著减少了类固醇治疗的持续时间 (12周而不是26周;p=0.001),没有显著的副作用.
结论:
- 系统性臭氧治疗 (OT) 提高了耐火IGM的完整反应率.
- OT有效地减少了长期使用类固醇治疗的需要.
- 臭氧治疗是一种安全,耐受性良好,有效的IGM补充治疗.
相关概念视频
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
351
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
351
Oxidative Cleavage of Alkenes: Ozonolysis
10.6K
In ozonolysis, ozone is used to cleave a carbon–carbon double bond to form aldehydes and ketones, or carboxylic acids, depending on the work-up.
Ozone is a symmetrical bent molecule stabilized by a resonance structure.
Ozone is a symmetrical bent molecule stabilized by a resonance structure.
10.6K
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
458
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
458
Asthma: Pathogenesis and Management
449
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
449
Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
266
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
266


