补充性水炎和牛皮:奇怪的夫妇
Laura Macca1, Federica Li Pomi1, Ylenia Ingrasciotta2
1Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina, Italy.
Frontiers in medicine
|July 24, 2023
概括
牛皮和补充性海炎 (HS) 经常同时发生,影响生活质量. 审查最近的文献强调了同时发生的HS和牛皮的治疗缺口,需要新的治疗策略.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 医学研究 医学研究
背景情况:
- 牛皮和补充性海炎 (HS) 是慢性炎症性皮肤疾病.
- 这些疾病可以并存,显著降低患者的生活质量.
- 了解这些自身免疫和自身炎症疾病之间的联系至关重要.
研究的目的:
- 综合当前关于牛皮和HS患者流行病学,病原和临床表现的知识.
- 对患有同时发生的牛皮和HS的个体进行治疗选择的审查.
- 确定研究缺口和管理这些双重条件的未来方向.
主要方法:
- 2017年至2022年间发表的科学文献的叙事综述.
- 使用PubMed数据库进行了搜索.
- 分析重点是病例报告和病例系列,详细介绍了患有牛皮和HS的患者.
主要成果:
- 在大多数报告的病例中,牛皮在HS之前发生;HS在较小的子集中在牛皮之前发生.
- 在治疗牛皮的生物治疗后,一些患者出现了矛盾的HS.
- 虽然生物药物在牛皮治疗方面取得了进步,但HS的类似进展仍然有限.
结论:
- 牛皮和HS的同时出现带来了独特的临床挑战.
- 目前治疗牛皮的治疗进展并没有转化为治疗HS的可比进展.
- 迫切需要新的治疗策略,以改善两种疾病患者的治疗结果.
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