在出生时注射维生素A可以改善羊羔的肌肉生长
Pengkang Song1, Xiaoyou Chen1, Jiamin Zhao1
1College of Animal Science, Shanxi Agricultural University, Taigu, Shanxi, 030801, China.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
|July 24, 2023
概括
新生儿肌肉内注射维生素A (视网醇) 增强了羊羔的生长率和肌肉发育. 这是通过提高卫星细胞的肌原潜力来实现的,导致肌纤维直径和体重增加.
科学领域:
- 动物科学动物科学
- 发展生物学 发展生物学
- 营养科学 营养科学
背景情况:
- 维生素A及其代谢物,视网酸 (RA),对于骨肌肉发育至关重要.
- 早期的营养对牲畜的长期生长和肌肉增长有重大影响.
研究的目的:
- 研究早期肌肉内注射维生素A对羊肉肌肉生长和发育的影响.
- 为了确定维生素A对绵羊骨肌细胞肌性能力的影响.
主要方法:
- 新生羊羔每周接受三周内肌肉内注射维生素A棕酸或玉米油 (对照).
- 肌肉样本在断奶时被分析,羊羔在8个月后被评估成长参数.
- 在体外研究中评估了骨肌源单核细胞的肌源性分化.
主要成果:
- 维生素A治疗显著增加了羔羊的生长率,最终体重和腰部眼部区域.
- 在接受维生素A治疗的羊羔中观察到长胸肌中肌纤维直径的增加.
- 维生素A上调了关键的肌源性调节基因 (PAX7,MYOD,MYOG) 并增强了体外肌管形成.
结论:
- 新生儿肌内注射维生素A可促进羔羊肌肉的生长.
- 维生素A增强了绵羊卫星细胞的肌性潜力,有助于增加肌肉质量.
- 早期补充维生素A可以作为提高羊肉生产效率的策略.
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