静止剂的使用会损害中风后患者的肌肉强度恢复,这些患者患有肉症
Ayaka Matsumoto1, Yoshihiro Yoshimura1, Fumihiko Nagano1
1Center for Sarcopenia and Malnutrition Research, Kumamoto Rehabilitation Hospital, Kumamoto, Japan.
Geriatrics & gerontology international
|July 24, 2023
概括
在中风患者中使用他类药物与肌肉强度恢复的减少有关,但与肌肉质量无关. 需要仔细考虑他类药物,以优化康复结果.
科学领域:
- 老年医学 老年医学
- 神经学 神经学
- 药理学 药理学是指药理学的学科.
背景情况:
- 肌肉健康和恢复在中风后至关重要,特别是在患有肉症的患者中.
- 对于这种人群的肌肉恢复,他类药物的影响尚不清楚.
研究的目的:
- 调查使用他类药物与在接受康复的中风患者肌肉力量和质量的恢复之间的关联.
主要方法:
- 一项回顾性队列研究分析了241名患有肉症的中风患者 (根据2019年亚洲肉症工作组标准诊断).
- 肌肉强度 (手握) 和质量 (骨肌肉质量指数) 在出院时被评估.
- 多变量分析检查了他类药物使用与康复结果的独立关联.
主要成果:
- 达丁类药物的使用独立地与下部手握强度有关 (P=0.032).
- 在他类药物使用和排放时的骨肌肉质量指数 (P=0.692) 之间没有发现显著的关联.
结论:
- 静止剂的使用可能会对接受康复的中风后肉患者的肌肉强度恢复产生负面影响.
- 在这种患者群体中使用他类药物的临床决定需要仔细考虑,以优化功能结果.
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